Lanolin Alcohol Property

Melting point:

>56°

Boiling point:

220-420℃ at 1.016hPa

Density 

0.953 at 20℃

vapor pressure 

3.6hPa at 20℃

solubility 

Practically insoluble in water, soluble in boiling anhydrous ethanol and in methylene chloride, slightly soluble in ethanol (90 per cent V/V).

Odor

amber hard waxy solid, char. odor

LogP

6.73-10.792

EPA Substance Registry System

Lanolin Simple Alcohols (8027-33-6)

Safety

HS Code 

1505009000

Hazard and Precautionary Statements (GHS)

Lanolin Alcohol Chemical Properties,Usage,Production

Chemical Properties

A pale yellow-colored, oily liquid with a faint characteristic sterol odor.

Chemical Properties

Lanolin alcohols is a pale yellow to golden brown-colored solid that is plastic when warm but brittle when cold. It has a faint characteristic odor.

Chemical Properties

Pale-yellow or brownish-yellow, brittle mass becoming plastic on heating.

Uses

lanolin alcohol is widely used as an emulsifier and emollient in water-in-oil systems. It absorbs a considerable amount of water that is then slowly released for moisturization purposes. Lanolin alcohol is a mixture of organic alcohols obtained from the hydrolysis of lanolin. It may cause skin sensitivity and allergic reactions.

Uses

emulsifier and emollient in cosmetic and pharmaceutical bases, topical drugs, furniture polish, leather, metal corrosion prevention, paper, inks, textiles, furs, cutting oils, waxes. lCU.

Uses

Wool alcohols have different types of alcohols (aliphatic, steroid, triterpenoid) present in wool fat. They are used as ointment base in cosmetic and pharmaceutical products

Definition

Lanolin Alcohol is a complex combination of organic alcohols obtained by the hydrolysis of lanolin.

Production Methods

Lanolin alcohols is dissolved in mineral oil.

Production Methods

Lanolin alcohols is prepared by the saponification of lanolin followed by separation of the fraction containing cholesterol and other alcohols.

Pharmaceutical Applications

Lanolin alcohols is an oily liquid used in topical pharmaceutical formulations and cosmetics as an emulsifying agent with emollient properties. It is used as a primary emulsifier in the preparation of water-in-oil creams and lotions and as an auxiliary emulsifier and stabilizing agent in oil-in-water creams and lotions.

Pharmaceutical Applications

Lanolin alcohols is used in topical pharmaceutical formulations and cosmetics as a hydrophobic vehicle with emollient properties, e.g. in preparations for dry skin and dry eyes. It is also used in the preparation of water-in-oil creams and ointments at concentrations as low as 2% w/w. The proportion of water that can be incorporated into petrolatum is increased threefold by the addition of 5% lanolin alcohols. Such emulsions do not crack upon the addition of citric, lactic, or tartaric acids.

Safety

Mineral oil and lanolin alcohols is generally regarded as an essentially nontoxic and nonirritant material. However, lanolin alcohols may be irritant to the skin and causes hypersensitivity in some individuals.

storage

Lanolin alcohols is stable and should be stored in a well-closed container in a cool, dry place.

storage

Lanolin alcohols may gradually undergo autoxidation during storage. Store in a well-closed, well-filled container, protected from light, in a cool, dry place. Normal storage life is approximately 2 years.

Incompatibilities

Incompatible with coal tar, ichthammol, phenol, and resorcinol.

Incompatibilities

Lanolin alcohols is incompatible with coal tar, ichthammol, phenol, and resorcinol.

Regulatory Status

Included in the FDA Inactive Ingredients Database (ophthalmic and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Nonmedicinal Ingredients.